UVA Health cardiologists have discovered a new way to track peripheral artery disease (PAD)

source:kempereng

 PAD is a serious medical condition characterised by atherosclerosis in the leg arteries that affects more than 200 million people worldwide.

source:wjgnet

The approach, according to the researchers, will greatly aid efforts to better understand the condition

source:wjgnet

which reduces blood flow to the limbs and improve treatment options for patients.

source:wjgnet

At the end of the exercise, the UVA researchers were able to use new magnetic-resonance imaging (MRI) techniques to understand the effects of PAD in the calves of patients with the disease and distinguish them from normal volunteers.

source:knerradio

The method they used, known as chemical exchange saturation transfer, or CEST

source:knerradio

CEST, they discovered, provided additional benefits without requiring highly specialised equipment that many hospitals and researchers do not have.

source:wjgnet

“The beauty of CEST is that it creates an image of energy stores in the muscle that we can match to images of blood flow,” said Christopher M. Kramer, MD, chief of UVA

source:wjgnet

CEST can also be combined with other magnetic resonance imaging methods that measure blood flow in the calf to help researchers better understand the effects of PAD.

source:wjgnet