Four new long-COVID studies reveal that 10% of French patients infected early in the pandemic still had symptoms 1 year later, SARS-CoV-2 can profoundly damage the brain for months, and very stressful events exacerbate persistent symptoms.

French specialists distributed another concentrate in JAMA Organization Open on 1-year paces of long Coronavirus among 53,047 grown-ups in three populace based bunches who took a cross country review from Apr 1 to Jun 30, 2020.

The specialists acquired blood tests for serologic affirmation of contamination from May 1 to Nov 30, 2020, and handled an online subsequent poll from Jun 1 to Sep 30, 2021.

In total, 3,972 people had tested positive for SARS-CoV-2, with 2,647 (66.6%) of them reporting at least one symptom during their infections. Of the 2,647 participants, 32.5% said they had at least one COVID-19 symptom for 2 months or longer

An estimated 97.5% of participants with weakness, 94.2% of those with impaired attention or concentration, and 77.5% of those with memory loss reported symptom resolution at 1 year.

Risk factors for lingering symptoms were age older than 60 years (hazard ratio [HR], 0.78), female sex (HR, 0.64), a history of cancer (HR, 0.61) or tobacco use (HR, 0.80), obesity (HR, 0.75), and more than four symptoms during infection (HR, 0.43).

These findings suggest the need to optimally manage comorbid conditions in individuals with long COVID to help reduce the duration of their symptoms."

Two studies presented this week at the Society for Neuroscience annual meeting in San Diego describe profound brain damage that lingers for months after COVID-19 infection.

Robyn Klein, MD, PhD, of Washington University and a panel moderator, said it isn't the first time that a flulike viral disease has been tied to an increased risk of dementia

The researchers said that pandemic-related stress may have unmasked previously undiagnosed mood disorders.